The University of Manchester PhD Studentship
Zebrafish As A Model Organism To Study Lowe Syndrome Faculty of Life Sciences Dr Martin Lowe Project to start September 2008
Lowe syndrome (LS) is an X-linked disorder affecting the brain, kidneys and eyes. It is caused by mutation of OCRL1, an inositol polyphosphate 5-phosphatase localised to the Golgi apparatus, endosomes and lamellipodia. OCRL1 appears to regulate actin dynamics and membrane traffic, but the mechanisms involved are poorly defined, and consequently we do not understand how loss of OCRL1 brings about the symptoms associated with LS. Progress in this area has been hampered by the lack of a model organism that recapitulates the syndrome pathology.
This project aims to utilise zebrafish (Danio rerio) as a model to investigate the role of OCRL1 in development, and to gain insight into how loss of the protein brings about the defects associated with LS. During the first part of the project ablation of OCRL1 by morpholino injection and over-expression of exogenous OCRL constructs will be performed, and the phenotypic consequences of these manipulations during early embryogenesis studied, focussing on the developing brain and kidney.
A variety of modern microscopy and molecular techniques will be used for this purpose.
The analysis will be then be expanded by obtaining zebrafish containing mutant OCRL1 alleles. This will permit a detailed investigation of the role of OCRL1 during both early and later stages of development, and hopefully serve as a valuable model for future screening of potential therapeutics.
For more details about this project please contact Dr Martin Lowe (martin.p.lowe@manchester.ac.uk ) or the Faculty of Life Sciences Graduate Office (Email: pg.lifesciences@manchester.ac.uk , Tel: 0161 275 5608)
This studentship is available to applicants from all nationalities.
Applicants will need a UK upper second class or first class honours degree (or overseas equivalent).
Full details of how to apply can be found at:
www.manchester.ac.uk/lifesciences/postgraduate/apply/
The University of Manchester PhD Studentship
Doctoral Studentships in Management Mathematics, Statistics or Computing
Doctoral Studentships in Management Mathematics, Statistics or Computing: Stipend up to £15,300 (+fees)
The only 6 star Management School outside London. Ranked joint 2nd in the UK and 9th in the world for PhD programmes by the FT 2006. The Department of Management Science (a part of the 6* rated Lancaster University Management School) is looking to recruit excellent doctoral students with a strong quantitative background including mathematics, statistics or computing.
Career prospects in management science and operational research are excellent with skills shortages in universities and research oriented organisations including private sector consultancies and government.
Topics include the analysis of queues and networks, optimisation and scheduling (applicable to logistics problems), forecasting and computer intensive methods including simulation and high performance computing.
Supervision is available in all areas of Management Science in one of the largest departments in Europe, see www.lums.lancs.ac.uk/Departments/ManSci/Research
Full scholarships are only available to home students and there are generous scholarships also available to EU and overseas students.
Find out more: www.lums.lancs.ac.uk/phd
Contact Gay Bentinck +44 (0)1524 592408: email g.bentinck@lancaster.ac.uk
Closing date for applications: Friday 7th March 2008
website link:
http://www.lums.lancs.ac.uk/files/13105.doc
or
http://www.lums.lancs.ac.uk/departments/ManSci/Research/
PhD Position available in Business Management H.N.B Garhwal University (India)
University Profile: University is residential cum affiliating with more than 150 affiliated colleges and institutions through out hilly of northern India spreading over an area of 30,000 Sq.kms. At present there are around 31 Departments in the University campus including the Department of Business Management. The University provides the most ideal conditions for serious study with the surrounding area abounding in natural grandeur with river Ganges flowing with its sylvan beauty and green forest accompanied by snow clad peaks invisible range offering a clean and fresh air, water besides a salubrious peaceful environment, all requisites for both learning and Yoga.
The Department of Business Management, set up by the university in the year 1996 with the approval of the All India Council for Technical Education and the then State Government of Uttar Pradesh is offering two – year full time MBA Degree course. The Department is functioning in a spacious, airy and well built building situated in the heart of the new University campus at Chauras across river Ganges. The class rooms are equipped with overhead/LCD projectors and other modern audio – video gadgets. Case studies, simulation exercises, classroom presentation, class lectures including group activities like seminars, workshops, guest lectures by outside experts, brain games, quizzes and field works are some of the techniques used in the course. Besides exercises relating personality development, enriching communication skills, and building team spirit are regular features. Meditation and the participation in cultural and social activities are unique features.
Vacancy: Two Positions Areas: Cross-culture study, Marketing Management, Customer Relationship Management, E-commerce and Entrepreneurship Development Duties: Research work, Project work, Teaching Assignment, field work etc Deadline: 31 April 2008 Eligibility: Master in Business Management and related Discipline Duration: 3 years
Applicants should send a CV (including details of 2 referees) and a personal statement in support of their application by post or email as given below address :
Contact Person: Dr Gajendra Singh, Associate Professor Department of Business Management Chauras Campus, H.N.B Garhwal University Srinagar Garhwal, Uttaranchal India-246147 Mobile: +919412029869 E-mail: gajendra_kashyap @ rediffmail.com
Scholarship in National Central University ( Taiwan)
National Central University (Taiwan) will visit University of Indonesia
on January 24th (next Thursday).
Prof. Benjamin Fong Chao, Dean and Professor of College of Earth Science will lead Sheng Jo-Pan (Professor of Civil Engineering), Lin Fa Cheng (Professor of Electrical Engineering), Emma (Assistant of International Affairs Division), Hadi Kuntjara (PHD student) for this visit.
We’d already asked the permission from University of Indonesia to invite students, alumni or staffs of ITB university who are interested in studying in Taiwan to join our interview at University of Indonesia.
For the qualified students, we wish to reserve scholarship and admission for them. As for NCU scholarships, a PhD student could get up to NT25,000/per month, Master: up to NT15,000/per month.
And the required documents for the interview:
• A copy of the student’s highest diploma
• A copy of transcript
• Additional relevant documents (research proposal, English or
Chinese proficiency certificate, thesis, publication and etc.)
Note: If students don’t have these documents, they are still welcome to
join us and submit the document at least April 20th.
http://www.ncu.edu.tw/e_web/admission.php
